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In clinical studies of Ulcerative Colitis, it helps both with healing the mucus lining of the colon as well as alleviating inflammation

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High-dose oral supplements (often 10002000 micrograms daily) or intramuscular injections (typically 1mg hydroxocobalamin) used to treat pernicious anaemia or deficiency states can temporarily elevate serum levels

Venous thromboembolism and hyperhomocysteinemia as first manifestation of pernicious anemia: a case series